ANAPLASTIC ASTROCYTOMA FROM THE PINEAL REGION, 4-YEAR FOLLOW-UP
CASE REPORT
DOI:
https://doi.org/10.31157/an.v29i1.473Keywords:
world health organization (WHO), Isocitrate dehydrogenase (IDH), magnetic resonance imaging (MRI) , Cerebrospinal fluid (CSF), Human chorionic gonadotropin beta fraction (HCG-b), Alpha feto protein (AFP)Abstract
Introduction.
The region pineal tumors represent a heterogeneous variety of primary neoplasms in the central nervous system. In this type of tumors the anaplastic astrocytoma have a low frequency in this region and the prognosis for survival in this type of tumor is relatively short.
Method.
We are present the case of 16 years old female with the histologic diagnosis of anaplastic astrocytoma from the pineal region with the diagnosis, treatment, follow-up, and survival for 4 years.
Discussion.
The anaplastic astrocytoma has a short survival according to our review, the parenchymal pineal tumors are less frequent than germinomatous tumors. The management chosen in this case was based in the international recommendations obtaining a 4-year follow-up and survival that make this case a success, contrary to the common prognosis of its histology.
Conclusion.
The anaplastic astrocytoma from the pineal region is a tumor whit low frequency. It executed a wide surgical resection in the presence of a highly malignant histology influences that the patient to present a disease-free survival above the average. We hope to contribute a case to the series of these rare tumor with a disease-free and stable evolution.
References
Tomomichi Kayahara, MD, PhD et. Al. “Pineal region pilocytic astrocytoma showing uncommon growth: a case report”, Radiology Case Reports 1 6 (2021) 2663–2667. https://doi.org/10.1016/j.radcr.2021.06.053. DOI: https://doi.org/10.1016/j.radcr.2021.06.053
Del Valle M, (2023) Pineal Gland Cancer - StatPearls - NCBI Bookshelf Publishing.
Stowe HB, Miller CR, Wu J, Randazzo DM and Ju AW (2017) Pineal Region Glioblastoma, a Case Report and Literature Review. Front. Oncol. 7:123. doi:10.3389/fonc.2017.00123. DOI: https://doi.org/10.3389/fonc.2017.00123
Randy S. D’Amico, M.D. et. Al. Pineal region glioblastomas display features of diffuse midline and non-midline gliomas, J Neurooncol. 2018 October ; 140(1): 63–73. doi:10.1007/s11060-018-2931-4. DOI: https://doi.org/10.1007/s11060-018-2931-4
Byung-Kyu Cho. et. Al. Pineal tumors: experience with 48 cases over 10 years, Child’s Nerv Syst (1998) 14: 53–58 © Springer-Verlag 1998. DOI: https://doi.org/10.1007/s003810050175
Choque Velasquez, Joham. Et. Al. Long term survival outcomes of pineal region gliomas, Journal of Neuro-Oncology (2020) 148:651–658 https://doi.org/10.1007/s11060-020-03571-z. DOI: https://doi.org/10.1007/s11060-020-03571-z
Monroy-Sosa Al. Et. Al. 2020, chapter 25: Management of pineal region tumors, Joham Choque Velasquez. Et. Al., Principles of neuro-oncology Brain & Skull Base. https://doi.org/10.1007/978-3-030-54879-7. DOI: https://doi.org/10.1007/978-3-030-54879-7
Roth, Jonathan. (2020), Pineal region tumors: an entity with crucial anatomical nuances. Child's Nervous System https://doi.org/10.1007/s00381-020-04826-w. DOI: https://doi.org/10.1007/s00381-020-04826-w
Favero, G.; Bonomini, F.; Rezzani, R. Pineal Gland Tumors: A Review. Cancers 2021, 13, 1547. https://doi.org/10.3390/ cancers13071547. DOI: https://doi.org/10.3390/cancers13071547
Jung Jang, Seon, (2012) A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal region: A case report and literature review, Neuropathology, doi:10.1111/j.1440-1789.2012.01347.x. DOI: https://doi.org/10.1111/j.1440-1789.2012.01347.x
Almahariq F, Raguz M, Romic D, Dlaka D, Oreskovic D, Sesar P, et al. A biphasic tumor in posterior cranial fossa and the pineal region in young adult. Surg Neurol Int 2020;11:64. DOI: https://doi.org/10.25259/SNI_288_2019
Sonabend A, Bowden S, Bruce J, (2016) Microsurgical resection of pineal region tumors, J Neurooncol DOI 10.1007/s11060-016-2138-5. DOI: https://doi.org/10.1007/s11060-016-2138-5
Winn R, (2023) Pineal Tumors, Neira J and Bruce J, Youmans & Winn neurological surgery, eighth edition, Elsevier. isbn: 978-0-323-66192-8.
Quiñones-Hinojosa A, (2022) SCHMIDEK & SWEET OPERATIVE NEUROSURGICAL TECHNIQUES INDICATIONS, METHODS, AND RESULTS, seventh edition, Elsevier, Philadelphia, PA. ISBN: 978-0-323-41479-1.
Greenberg Mark S, (2020) Handbook of neurosurgery / 9th edition. New York : Thieme. ISBN 978-1-68420-137-2.
Cohen Alan R, (2022) Brain tumor in children. N Engl J Med 2022;386:1922-31. DOI: 10.1056/NEJMra2116344. DOI: https://doi.org/10.1056/NEJMra2116344
Mahmoud AB, Ajina R, Aref S, Darwish M, Alsayb M, Taher M, AlSharif SA, Hashem AM and Alkayyal AA (2022) Advances in immunotherapy for glioblastoma multiforme. Front. Immunol. 13:944452. doi: 10.3389/fimmu.2022.944452 DOI: https://doi.org/10.3389/fimmu.2022.944452
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September 2022-present © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January-September 2022 © The authors. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January 2014-December 2021 © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.