Uso de tenecteplasa en el manejo del ictus isquémico agudo: ¿realmente es seguro y tiene beneficios frente a otras terapias?

Patrick Junior Brett Cano; Adrián David Cano Carmona; German Andres Guevara Lizarazo; Duvier Fabián Meza Fandiño; Michael Ortega-Sierra

doi:10.31157/an.v28i3.468

Use of tenecteplase in the management of acute ischemic stroke: Is it really safe and beneficial compared to other therapies?

Authors

Patrick Junior Brett Cano Department of Medicine, University of Sinú, Cartagena, Colombia https://orcid.org/0000-0003-0105-5217
Adrián David Cano Carmona Department of Medicine, University of Cartagena, Cartagena, Colombia https://orcid.org/0009-0001-0508-2637
German Andres Guevara Lizarazo Department of Medicine, University of Pamplona, Cúcuta, Colombia https://orcid.org/0000-0003-0375-760X
Duvier Fabián Meza Fandiño Department of Medicine, University of Boyacá, Tunja, Colombia https://orcid.org/0000-0001-9772-0618
Michael Ortega-Sierra Department of Neurosurgery, Lisandro Alvarado Central Western University - Antonio María Pineda Central Hospital, Barquisimeto, Venezuela https://orcid.org/0000-0002-3091-9945

DOI:

https://doi.org/10.31157/an.v28i3.468

Keywords:

Tenecteplasa, ictus, trombolisis, Seguridad, eficacia

References

Pan American Health Organization. Burden of Neurological Conditions [Internet]. [Consulted 22 Mar 2023]. Available in: https://www.paho.org/en/enlace/burden-neurological-conditions

Lozada-Martínez I, Maiguel-Lapeira J, Torres-Llinás D, Moscote-Salazar L, Rahman MM, Pacheco-Hernández A. Letter: Need and Impact of the Development of Robotic Neurosurgery in Latin America. Neurosurgery. 2021; 88(6):E580-E581. doi: 10.1093/neuros/nyab088 DOI: https://doi.org/10.1093/neuros/nyab088

Vaishnav AG. Is Tenecteplase a Viable Alternative to Alteplase in the Treatment of Acute Ischemic Stroke? Ann Indian Acad Neurol. 2022; 25(5):794-795. doi: 10.4103/aian.aian_668_22 DOI: https://doi.org/10.4103/aian.aian_668_22

Wang Y, Li S, Pan Y, Li H, Parsons MW, Campbell BCV, et al. Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial. Lancet. 2023; 401(10377):645-654. doi: 10.1016/S0140-6736(22)02600-9 DOI: https://doi.org/10.1016/S0140-6736(22)02600-9

Kvistad CE, Næss H, Helleberg BH, Idicula T, Hagberg G, Nordby LM, et al. Tenecteplase versus alteplase for the management of acute ischaemic stroke in Norway (NOR-TEST 2, part A): a phase 3, randomised, open-label, blinded endpoint, non-inferiority trial. Lancet Neurol. 2022; 21(6):511-519. doi: 10.1016/S1474-4422(22)00124-7 DOI: https://doi.org/10.1016/S1474-4422(22)00124-7

Roaldsen MB, Eltoft A, Wilsgaard T, Christensen H, Engelter ST, Indredavik B, et al. Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. Lancet Neurol. 2023; 22(2):117-126. doi: 10.1016/S1474-4422(22)00484-7 DOI: https://doi.org/10.1016/S1474-4422(22)00484-7

Kobeissi H, Ghozy S, Turfe B, Bilgin C, Kadirvel R, Kallmes DF, et al. Tenecteplase vs. alteplase for treatment of acute ischemic stroke: A systematic review and meta-analysis of randomized trials. Front Neurol. 2023; 14:1102463. doi: 10.3389/fneur.2023.1102463 DOI: https://doi.org/10.3389/fneur.2023.1102463

Bonifacio-Delgadillo DM, Castellanos-Pedroza E, Martínez-Guerra BA, Sánchez-Martínez CM, Marquez-Romero JM. Delivering acute stroke care in a middle-income country. The Mexican model: "ResISSSTE Cerebro". Front Neurol. 2023; 14:1103066. doi: 10.3389/fneur.2023.1103066 DOI: https://doi.org/10.3389/fneur.2023.1103066

Cano-Nigenda V, Castellanos-Pedroza E, Manrique-Otero D, Méndez B, Menéndez-Manjarrez MF, Toledo-Treviño R, et al. Barriers to Optimal Acute Management of Stroke: Perspective of a Stroke Center in Mexico City. Front Neurol. 2021; 12:690946. doi: 10.3389/fneur.2021.690946 DOI: https://doi.org/10.3389/fneur.2021.690946

Additional Files

PDF-ESP (Español (España))

Published

2023-04-24

How to Cite

Brett Cano, P. J., Cano Carmona, A. D., Guevara Lizarazo, G. A., Meza Fandiño, D. F., & Ortega-Sierra, M. (2023). Use of tenecteplase in the management of acute ischemic stroke: Is it really safe and beneficial compared to other therapies?. Archivos De Neurociencias, 28(3). https://doi.org/10.31157/an.v28i3.468

Download Citation

Issue

Vol. 28 No. 3 (2023)

Section

Letter to Editor

License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

September 2022-present © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.

January-September 2022 © The authors. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.

January 2014-December 2021 © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.