Mania associated with thymoma. A case report in Colombia.
DOI:
https://doi.org/10.31157/an.v28i4.457Keywords:
Mania, Autoimmune encephalitis, Paraneoplastic syndrome, ThymomaAbstract
Antibody-mediated encephalitis may not be easily recognizable and has a heterogeneous and polymorphous presentation at the crossroads of oncology and neuropsychiatry. In this article, a case of 75-year-old female with an advanced Thymoma is presented. This patient debuts subacutely with neuropsychiatric symptoms, with positive findings in neurologic and mental exams, and laboratory results. The initial treatment worsened the affective symptoms, which required a switch to high doses of antipsychotic medication. This case allows for discussion of pathophysiological, clinical, diagnostic and treatment aspects of a patient with an unresectable neoplasia associated with neuropsychiatric symptoms. Additionally, immune treatment generates clinical difficulties.
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Copyright (c) 2022 Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez
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September 2022-present © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January-September 2022 © The authors. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January 2014-December 2021 © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
