Development of the nigrostriatal dopaminergic pathway

Authors

  • M. Gómez-Chavarín
  • R. Santos-Echeverria
  • M. García-García
  • C. Torner-Aguilar
  • A. Báez-Saldaña

DOI:

https://doi.org/10.31157/an.v19i2.40

Keywords:

neuronal circuits, dopaminergic pathway, basal ganglia, median spiny neurons.

Abstract

Brain circuits at birth are immature and refined by intrinsic mechanisms and effects of the microenvironment. Immature neural circuits are also plastic and therefore vulnerable to the impact of external or environmental factors which can alter its functionality and result in the expression of circuits or aberrant behavior associated with pathologies. Functional abnormalities of basal ganglia can cause some neuropsychiatric pathologies and behavioral manifestations. Anatomy and functioning of the corticostriatals circuits are known in the adult animal but, is there evidence of its maturation is completed in late stages of postnatal development?

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Published

2014-06-01

How to Cite

Gómez-Chavarín, M., Santos-Echeverria, R., García-García, M., Torner-Aguilar, C., & Báez-Saldaña, A. (2014). Development of the nigrostriatal dopaminergic pathway. Archivos De Neurociencias, 19(2), 95–103. https://doi.org/10.31157/an.v19i2.40

Issue

Vol. 19 No. 2 (2014)

Section

Evidence synthesis

License

Copyright (c) 2014 Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

September 2022-present © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.

January-September 2022 © The authors. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.

January 2014-December 2021 © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.