Psychogenic non-epileptic seizures following COVID-19 vaccine: A report of two cases in Colombia




Vaccination, psychogenic non epileptiform seizures, SARS-CoV-2, COVID-19, pandemic, post-vaccine events.


The novel coronavirus SARS-CoV-2 has caused the death of more than 5 million of people worldwide. Vaccination is the best strategy for controlling the pandemic with an estimated of more that 4 million of people completely vaccinated. The reported adverse events secondary to vaccines against SARS-CoV-2 are mainly mild and moderate, however, there are raising concerns about more severe and long-term outcomes, as well as neurological complications due to the vaccine.

We present two cases of psychogenic non epileptiform seizures (PNES) in Colombian female patients, following vaccination against Covid-19. There is no evidence of similar adverse reactions reported on the literature and thus, we decided to report these events in order to help clinicians in recognizing early and properly all the possible neurological manifestations related to this novel approach, that aimes to eradicate the viruses which has come along with worldwide devastating consequences in terms of health and social issues.

Author Biographies

Julio Cesar Villalobos-Comas, Universidad Nacional Autónoma de México. Liga Cordobesa contra la Epilepsia, Córdoba, Colombia

ORCID: 0000-0002-9200-2518

Edgard Eliud Castillo-Támara, Universidad de Buenos Aires, Buenos Aires, Argentina. Director of Neurology program, Universidad del Sinú “Elías Bechara Zainum”, Cartagena Colombia

ORCID: 0000-0001-8084-8586


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How to Cite

Villalobos-Comas, J. C., Castillo-Támara, E. E., Montaño Lozada, J. M., & Cardona Moica, S. M. (2022). Psychogenic non-epileptic seizures following COVID-19 vaccine: A report of two cases in Colombia. Archivos De Neurociencias, 27(4).



Case report