Feasibility of a culture-specific Moroccan Smell Identification Test (MoroSIT): a proposal using the case of Parkinson disease


  • Mohamed Chraa Neuroscience Research laboratory, Faculty of Medicine and Pharmacy of Marrakesh, Cadi Ayyad University
  • Hanane Imizgue Neuroscience Research laboratory, Faculty of Medicine and Pharmacy of Marrakesh, Cadi Ayyad University
  • Raymond Klevor Mohammed VI University Medical Center
  • Najib Kissani Neuroscience Research laboratory, Faculty of Medicine and Pharmacy of Marrakesh, Cadi Ayyad University




Parkinson disease, Biomarker, Olfaction, Sniff test, Indigenous plants


Introduction: Olfactory problems are frequent in Parkinson disease. Their early onset relative to motor problems makes them a potential biomarker for the disease, yet no culture-specific standardized tests exist in Morocco.

Aim: To use indigenous plant extracts generated in our laboratory to investigate olfactory impairment in patients with Parkinson disease.

Method: Our study is a cross-sectional case-controlled analytical investigation in a group of 69 patients with Parkinson disease and another group of 66 healthy volunteers in order to assess odor threshold, odor identification, and odor discrimination in these two groups using Mentha pulegium and Lavandula latifolia extracts.

Results: We found a marked decrease of the threshold of odor detection in patients compared to controls (p<0.001). A statistically significant difference was found between the ability to discriminate odors, with more patients with Parkinson disease unable to distinguish between odors (p<0.001). For the odor identification test, 70% of control subjects versus 36% of patients were able to correctly identify the test products. The difference was statistically significant (p<0.001).

Conclusions: Our study points to the potential for the elaboration of a standardized smell identification screening battery using indigenous products with which patients are familiar.


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How to Cite

Chraa, M. ., Imizgue, H. ., Klevor, R., & Kissani, N. . (2022). Feasibility of a culture-specific Moroccan Smell Identification Test (MoroSIT): a proposal using the case of Parkinson disease . Archivos De Neurociencias, 28(1). https://doi.org/10.31157/an.v28i1.368



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