Effect of Perinatal asphyxia and body hypothermia on hearing evocated potentials and development in the first two years of life

Authors

  • Karla Maria Soler Limon NATIONAL INSTITUTE OF PEDIATRICS
  • Gabriela Romero Autonomous Metropolitan University - Xochimilco Unit, Department of Health Care
  • Pedro Valentín Romero Gutiérrez Autonomous Metropolitan University - Xochimilco Unit, Department of Health Care
  • Alberto Orozco Gutiérrez La salle university. Mexican School of Medicine
  • Claudia Laura Calderon Jimenéz General Hospital Ajusco Medio “Dra. Obdulia Rodríguez Rodríguez ”, Neonatology Service
  • Iván Rolando Rivera González National Institute of Pediatrics, Center for Neurodevelopment Research

DOI:

https://doi.org/10.31157/an.v27i2.311

Keywords:

Perinatal asphyxia, Hypoxic Ischemic Encephalopathy, hypothermia, child development, PEATC

Abstract

ABSTRACT. Perinatal asphyxia is associated with a high risk of death as well as a risk of deterioration of neurodevelopment both early and late, in addition, severe episodes can have an important effect on auditory function, cochlear damage and retrocochlear neuronal lesions. With the use of body hypothermia therapy as a neuroprotector in the first 72 hours, it has been possible to improve the survival of neonates, as well as the neurodevelopmental results in cases with moderate to severe HIE. Objective To describe the characteristics of the AEPP of infants with moderate and severe HIE treated with body hypothermia and their relationship with the development achieved at one and two years of age. Material and Method, 51 children were studied who underwent PEATC at 3, 6 and / or 12 months of age and their development was evaluated at 12 and 24 months of age with the Gesell, Bayley II and Bayley III tests. Results The PEATC values ​​were similar to those observed in healthy children and were significantly correlated with development at both ages, especially waves I and III. The Normal / Altered categories in the PEATC showed differences of one standard deviation in the developmental score. Conclusions the PEATC showed a relationship with later development; the characterization of normality / alteration that we propose allowed to show the PEATC as an indicator of risk for development, even before the frank damage in the auditory pathway.

Author Biographies

Gabriela Romero, Autonomous Metropolitan University - Xochimilco Unit, Department of Health Care

Physician, specialist in Clinical Neurophysiology, PhD in Biological Sciences; Professor of the Bachelor of Medicine and the Master of Neurological Rehabilitation, both at the Universidad Autónoma Metropolitana

Pedro Valentín Romero Gutiérrez, Autonomous Metropolitan University - Xochimilco Unit, Department of Health Care

PHYSICIAN IN SOCIAL SERVICE, ASSIGNED TO RESEARCH PROJECTS, IN THE AREA OF NEUROPHYSIOLOGY OF THE CENTER OF NEURODESARROLLO RESEARCH

Alberto Orozco Gutiérrez, La salle university. Mexican School of Medicine

SPECIALIST DOCTOR IN NEONATOLOGY; PROFESSOR OF NEONATOLOGY IN THE BACHELOR'S DEGREE IN MEDICINE, LA SALLE UNIVERSITY

Claudia Laura Calderon Jimenéz, General Hospital Ajusco Medio “Dra. Obdulia Rodríguez Rodríguez ”, Neonatology Service

MEDICAL SPECIALIST IN NEONATOLOGY, HEAD OF THE NEONATOLOGY SERVICE AT THE AJUSCO MEDIO GENERAL HOSPITAL FROM 2012 TO 2015; PROFESSOR OF THE MEDICINE PROGRAM, LA SALLE UNIVERSITY

Iván Rolando Rivera González, National Institute of Pediatrics, Center for Neurodevelopment Research

PEDIATRIC DOCTOR, MASTER IN NEUROLOGICAL REHABILITATION, DOCTOR IN ANTHROPOLOGY; RESEARCHER IN MEDICAL SCIENCES "D" AND HEAD OF THE NEURODEVELOPMENT RESEARCH CENTER (2015 TO DATE)

Published

2022-05-11

How to Cite

Soler Limon, K. M., Romero Esquiliano, G. del P., Romero Gutiérrez, P. V., Orozco Gutiérrez, A., Calderon Jimenéz, C. L., & Rivera González, I. R. (2022). Effect of Perinatal asphyxia and body hypothermia on hearing evocated potentials and development in the first two years of life: . Archivos De Neurociencias, 27(2), 5–10. https://doi.org/10.31157/an.v27i2.311

Issue

Section

Original Articles