Foreign accent syndrome in Multiple Sclerosis, review and case presentation.
DOI:
https://doi.org/10.31157/an.v26i3.225Keywords:
demyelinating, multiple sclerosis, foreign accent syndrome, cortical symptoms, review.Abstract
Introduction. Foreign Accent Syndrome (FAS) is a rare entity. Patients develop changes in rhythm and tone of speech (prosody), perceived as a different accent than their native language. There are three types of FAS: neurogenic, psychogenic and mixed. FAS is rare in MS, and even more so as a debut symptom.
Objective. Review of FAS, types, pathophysiology, presentation in MS and evolution.
Summary. Cortical lesions in MS are correlated with cognitive impairment, motor disability, psychiatric symptoms, language disorders, speech impairment, and seizures. Aphasia is a rare symptom in MS (0.7 - 3%). Most of the published cases of FAS have suffered injury in the dominant hemisphere, in the prerrolandic cortex and adjacent areas, frontal motor association areas, in the putamen, basal ganglia, and the posterior fossa (protuberance, cerebellum). Different etiologies have been reported, vascular being the most frequent. We present the case of a 44-year-old woman who debuted with FAS, previously interpreted as a brain ischemia and finally diagnosis as multiple sclerosis.
This case had partial improvement of the symptoms after phonoaudiologic rehabilitation.
Conclusions. FAS is a rare form of MS debut, as cortical symptoms are atypical relapses. Demyelinating etiology should be considered in young patients with few or without vascular risk factors, and must be supported by complementary neuroimaging studies.
Downloads
Additional Files
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez
This work is licensed under a Creative Commons Attribution 4.0 International License.
September 2022-present © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January-September 2022 © The authors. Open access articles under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. No commercial re-use is allowed.
January 2014-December 2021 © Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez. Open access articles under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.